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100 mM glycine-HCl pH 2.5

Elution of antibodies from protein A/G columns.

Component100 mL500 mL1 L
Glycine0.7507 g3.754 g7.507 g
HCl (1 M)approximate; finish with a pH meter4.145 mL20.73 mL41.45 mL
Final volume with water100 mL500 mL1 L
  1. Dissolve Glycine in about 80 % of the final volume of purified water.
  2. Adjust to pH 2.5 at 25 °C with HCl (1 M), adding slowly while stirring.
  3. Make up to the final volume with water.
  4. Filter-sterilise (0.22 µm) and store at 4 °C.