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Buffer recipes

Masses and titrant volumes for common buffers at 25 °C. Open any recipe in the calculator to change concentration, pH, volume or temperature.

TrispKa 8.07

HEPESpKa 7.48

MESpKa 6.1

MOPSpKa 7.2

PIPESpKa 6.76

PhosphatepKa 2.15 / 7.2 / 12.35

AcetatepKa 4.76

CitratepKa 3.13 / 4.76 / 6.4

GlycinepKa 2.35 / 9.78

Carbonate / bicarbonatepKa 6.35 / 10.33